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Since GLP-1 receptor agonists enhance the effect of GLP-1, but only when the sugar is high, they have a lower risk of causing low blood sugar (hypoglycemia) than some medications

Clinical studies report participants losing 15 to 20 percent of their body weight over 72 weeks

doi: 10.3389/fpls.2023.1204723, 85 MajernikovaN.den DunnenW.DolgaA

Semaglutide is generally well-tolerated, but as with any medication, some patients experience mild side effects particularly during the dosage adjustment phase

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This is due to its stable and sustained GH release profile