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For those seeking alternatives, options like Tirzepatide and Retatrutide are available
They were all American, one from Harvard Medical School
One important note: this combination does not affect cortisol or prolactin levels, which is relevant for menopausal women who may already be dealing with cortisol dysregulation
Siasos G, et al
In rodents, the GLP-1R is now known to be expressed in the atrium but, unlike in humans and non-human primates, not in in the SA node (103)
Some specific locations of these receptors are in the vascular smooth muscle, cardiomyocytes, endocardium and coronary endothelium/smooth muscle
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