However, univariate GLM with age as a covariate revealed other neurochemical abnormalities in the pgACC, notably in concentration of lactate (F = 4.684, p = 0.013) (Fig
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Cardiovascular Safety In the PROactive trial, 5,238 patients with type 2 diabetes mellitus and a history of macrovascular disease were randomized to pioglitazone (N=2,605), force-titrated up to 45 mg daily or placebo (N=2,633) in addition to standard of care
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Many patients find a lower dose provides adequate weight loss with tolerable constipation