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PDE4 inhibitors, including CC-11050, CC-3052, and roflumilast, when combined with INH, have been shown to reduce the lung bacillary burden, lung pathology, and fibrosis, as well as the size and number of lung granulomas in M.tb -infected rabbits and in both acute and chronic TB mouse models [35, 108, 109]
Peringatan dan Perhatian Menggunakan Glutathione Informasikan ke dokter saat Anda ingin mengonsumsi obat ini bila Anda sedang dalam kondisi: Memiliki alergi terhadap obat ini atau bahan lain yang terkandung di dalamnya Punya kondisi kesehatan tertentu seperti penyakit kronis menahun Sedang minum obat-obatan atau suplemen lain baik untuk pemakaian oral/topikal Sedang mengandung, menyusui, atau sedang merencanakan kehamilan Efek Samping dan Bahaya Glutathione Sedikitnya riset atau studi terkait glutathione, maka masih belum diketahui secara pasti apa saja efek samping dari glutathione
Moreover, the combined treatment of these two agents proved more effective than single interventions, suggesting potential synergistic effects (Mobasher et al., 2022)
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