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What were the most common side effects of AOD-9604 in clinical trials
Liu M et al
Irwin K, Sexton C, Daniel T, Lawlor B, Naci L
A phase 1 trial enrolling participants with BMI 3040 kg/m 2 and without T2D shows that when given in multiple ascending doses, the mean body weight losses by day 85 range from 7.2% to 14.5% at the lowest (140 mg) and highest (420 mg) doses, respectively, compared to weight gain of 1.5% for the placebo group (70)
The Mod denotes a few amino acid modifications that help the peptide resist enzymatic breakdown
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