[22] [23] The pain relief paracetamol provides in osteoarthritis is small and clinically insignificant
Since, the standards for glutathione assay and the samples are treated with 4-vinylpyridine at same concentrations and same conditions, the marginal negative effect of 4-vinylpyridine is seen in glutathione standards and samples equally and thus treatment with 4-vinylpyridine does not interfere with estimation of glutathione concentration in the samples
Brains were cleared using iDISCO standard protocol 62,63
Unfortunately, the small sample size and the lack of thyroid function data of enrolled patients prevent drawing conclusions on this possible effect
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