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Additionally, study designs, dosages, and participant characteristics differ across trials, making it difficult to draw definitive conclusions
The anti-fatigue mechanisms of carnosine operate through multiple pathways targeting muscle cells and metabolic function
Rigorous human studies are required to determine safety parameters, mechanistic specificity, and potential translational relevance before any clinical applications can be considered
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A gene profiling study found that GHK modulated expression of 4,048 human genes at a very low concentration of 1 micromolar, with significant upregulation of genes involved in tissue remodeling and anti-inflammatory responses 15