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This may contribute to sex-based differences in immune function and disease susceptibility, while in females, the same mechanism may lead to heightened immune responses and an increased risk of autoimmunity [98, 110]
However, it also has been found to be associated with insulin resistance syndrome including obesity, fat distribution, hypertension, dyslipidemia, and cardiovascular disease [48]
Meister, Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione
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