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Two key enzymes are implicated in PUFA-PE synthesis, including acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) [75]
It's an active area of research interest because dihexa promotes new synaptic connections, but it is not a proven or approved treatment for cognitive decline
The clinical logic is sound
Lithium and valproate both promote significant weight gain through multiple pathways
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It has not been evaluated by the Food and Drug Administration and is not approved for therapeutic, diagnostic, or human application of any kind
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