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Sterile, nonpyrogenic water containing 0.9% benzyl alcohol as a bacteriostatic preservative

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FOXOs: signalling integrators for homeostasis maintenance

This substitution may potentially increase the resistance of the peptide to enzymatic degradation and improve its stability

Geroprotective and Anticarcinogenic Activity Lifetime Murine Studies Long-term studies in mice demonstrated that DSIP administration over a lifetime decreased total spontaneous tumour incidence 2.6-fold compared to untreated controls, slowed age-related switching-off of oestrous function, decreased the frequency of chromosome aberrations in bone marrow cells by 22.6%, and increased maximum lifespan by 24.1% compared to control groups a multi-parameter geroprotective profile that is among the most striking reported for any short regulatory peptide, and that has generated sustained interest in the DSIP analogue research field

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