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Neuroscience, 169(2), 674-682
They are substances that help neutralize free radicals and protect the cells from damage caused by free radicals
Furthermore, specific alterations in microRNA (miRNA) expression profiles (e.g., miR-146a, miR-27b-3p) have been identified as sensitive indicators of epigenetic disruption, modulating downstream pathways involved in cell cycle control, metabolism, and stress responses [165,166,167]
Scoliosis in Friedreichs ataxia: longitudinal characterization in a large heterogeneous cohort
When these proteins are abnormally expressed, the overload cytosolic free ferrous iron leads to intracellular ROS accumulation via the Fenton reaction, which eventually promotes lipid peroxides formation and ferroptosis occurrence (186)
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