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Reduce UV-induced cellular damage (sunburn cells)

Pan Y, Oprysko PR, Asham AM, Koch CJ, Simon MC

Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3

Mol Biol Rep 2013;40(4):3299-3313

Expected results and realistic timelines Setting realistic expectations is important for maintaining protocol adherence

Subunit vaccines, composed of one or a few mycobacterial antigens delivered with a platform of choice, have better safety profiles than live attenuated vaccines ( MTB ( MTB antigens linked to MHC-I in primary human macrophages sourced from six donors with LTBI ( MTB challenge model