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This effect is dose-dependent and more common during the loading phase when daily doses are at their highest
When pregnancy is recognized, advise the pregnant patient of the risk to a fetus
Without that built-up tolerance, the medication can slow your gastric emptying too aggressively
The rationale is that the two medications work through completely different mechanisms, phentermine through norepinephrine release and semaglutide through GLP-1 receptor activation, so they could theoretically complement each other
SIG (sample or Starter Rx): Take one tablet by mouth every morning on an empty stomach with up to 4 oz of water
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