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N Engl J Med 377(1):1327 Wilding JPH et al (2021) Once-weekly semaglutide in adults with overweight or obesity

Beyond pharmacotherapy, emerging evidence suggests that gut microbiotaderived metabolites and postbiotics, such as short-chain fatty acids (SCFAs) and tryptophan-derived indoles, can modulate enteroendocrine function, inflammatory tone, insulin sensitivity, and gutbrain communication

doi: 10.1016/s0140-6736(66)92982-5 12 DruckerDJ

About Pomegranate Health Pomegranate Health is a Florida-based telehealth coordinator

An important international trial shows that combining cagrilintide and semaglutide helps adults with obesity achieve more dramatic weight loss and better metabolic health than current single-drug therapies

Studies utilizing mouse models of T2DM-associated cognitive dysfunction and high glucose-stimulated PC12 cell models have established a link between DACD pathogenesis and ferroptosis mediated by GPX4 suppression