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For a full breakdown of how tirzepatide works as a dual GIP/GLP-1 agonist, see the overview guide
Summary: In Phase 2 clinical trials, retatrutide was typically initiated at 2 mg once weekly via subcutaneous injection, with gradual dose escalation over several months under close medical supervision
On average, many achieve meaningful reductions in both body weight and waist circumference when combining medication with lifestyle changes
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