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showed that FOXO4 expression is upregulated in irradiated-induced senescent IMR90 cells and that the protein binds to p53, inhibiting the role of this last one in apoptosis induction
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Conversely, a knockdown of Bcl-2 provoked a decrease in mGSH and a concomitant oxidative stress sensitization (Wilkins et al., 2014)
By weeks 3-4, skin texture changes become more apparent
Nature 444 (7119), 624628
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