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Since there is no consensus regarding the cutoff value of GPX4 protein expression, we determined negative if less than 5% of tumor cell were stained
Scenario 3: Perimenopausal woman on oral HRT switching to GLP-1 You are 47, in perimenopause, currently taking oral estradiol 1 mg daily and oral micronized progesterone 100 mg nightly
The Food and Drug Administration (FDA) has approved three GLP-1s for obesity-related treatment, including Saxenda (liraglutide), Wegovy (semaglutide), and Zepbound (tirzepatide)
However, like any medication, they can cause side effects
Safety & Side Effects While generally well-tolerated, common side effects include "mild nausea, digestive discomfort, and appetite suppression." These effects typically "subside over time as you acclimate to the medication." 3