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The Genetic Approach: A Novel Insight The researchers at the University of Hong Kong used a method called Mendelian randomization, which analyzes naturally occurring genetic differences to mimic the effects of a drugin this case, GLP-1 receptor agonists

Another study reported that the bitter taste of berberine causes the activation of bitter taste receptors (TAS2Rs), which further activates the downstream signalling pathway, leading to enhanced GLP-1 secretion 4

These hypotensive episodes were most common among patients aged 65 and older and those with diabetes, the scientists found

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