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[Updated 2022 Nov 28]

In addition, we did not conduct metabolite analysis in tissues, especially in target organs, owing to the small sample size

Theoretical risks of sustained angiogenic stimulation (promoting vascular supply to undetected pathological tissue) grow proportionally with the duration of use, as cumulative VEGF upregulation exceeds the controlled, injury-localized window intended by short-cycle research protocols

Why this matters for the research community Regardless of the final outcome, the vote signals a shifting regulatory conversation around peptides that were pushed to the margins in 2023

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