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Wilhelms DB, Kirilov M, Mirrasekhian E, Eskilsson A, Kugelberg UO, Klar C, et al

this occurs because there is not enough vitamin B12 in the diet or poor absorption Pernicious anemiaa type of megaloblastic anemia caused by a lack of intrinsic factor so that vitamin B12 is not absorbed Fatigue, weakness Nerve damage with numbness, tingling in the hands and legs Memory loss, confusion Dementia Depression Seizures Toxicity Toxicity Vitamin B12 is a water-soluble vitamin, so any unused amount will exit the body through the urine

SIRT1 is critical in slowing down aging

Pregnant or breastfeeding individuals There isnt enough human data to confirm astaxanthins safety during pregnancy or breastfeeding, so most experts recommend avoiding supplementation during these periods

Some people splitting into 2x/week report fewer GI sides, but it's not required

NAD+ levels naturally decline with age