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Role of Circadian Rhythm in GLP-1: The effectiveness of GLP-1 is also influenced by our bodys natural daily rhythms

The authors offer this explain their findings this way: Here we demonstrate that tirzepatide, a dual GLP-1R/GIPR agonist, affects alcohol intake and alcohol-related responses across both sexes in rodents

This ensured unbiased allocation and reduced potential confounding factors

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