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Superoxide generated in the mitochondrial matrix by these sites is converted to hydrogen peroxide by manganese-dependent superoxide dismutase 2 (SOD2)
In line, lipid ROS accumulated in Gclc -deficient cells at steady state (Supplementary Fig
This compound is a cyclic hydroxylamine that is oxidized upon the reaction with superoxide to generate a more stable radical called nitroxide
In: SarkarTHamadAChatterjeeA, editors
Jowsey, Glutathione transferases
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