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As blood sugar levels are reduced, it becomes easier to burn more body fat
This triple-action mechanism distinguishes retatrutide from existing approved therapies such as semaglutide (a GLP-1 receptor agonist) and tirzepatide (a dual GLP-1/GIP agonist)
The exendin 939 concentration used in this experiment was approximately 30 times higher than its IC 50 value for CAP-induced TRPV1 activation, indicating the mode-selective characteristics of exendin 939
CDC NCHS Data Brief Use of GLP-1 Receptor Agonists Among Adults With Diagnosed Diabetes (cdc.gov), August 2025
Efficacy endpoints were analyzed using data from all randomized participants
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