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Keywords 0 7 INTRODUCTION Cardiovascular diseases (CVD) are the leading cause of death worldwide, and despite major advances in CV medicine, advancing age remains the major CVD risk factor [1-3]

Systemic glutathione as a skin-whitening agent in adult

Ursini et al., 1999)

We thus next asked whether H 2 O 2 also more efficiently elicits GSSG production in the matrix than in the cytosol and if so, what enzymes are important for catalyzing the glutathionemediated reduction of H 2 O 2

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Ethics declarations Conflict of interest SC received lecture or consultancy fees from AstraZeneca, Boehringer Ingelheim, Eli Lilly, MSD, Novo Nordisk