After 12-18 hours centrilobular hepatic necrosis occurs which may be accompanied by renal tubular necrosis and hypoglycaemia that may progress to coma
To ensure safety and effectiveness, supplementation protocols should be tailored to meet the unique needs of each individual
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The vial math below assumes a 5 mg vial reconstituted with 2.0 mL BAC water (2.5 mg/mL) for the 2.4 mg/week target