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In late 2023, the FDA added more than a dozen peptides including both BPC-157 and thymosin alpha 1 to its list of substances that should not be compounded because the agency has identified potential significant safety risks. For BPC-157, the agency warned that the peptide could trigger an immune response

However, some regions have lower limits, such as 0.05% or even zero-tolerance policies for certain drivers

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This underscores the importance of patient-reported outcomes in guiding management strategies

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