This protects against side effects, but it also means appetite suppression builds over time rather than appearing suddenly
Impaired Energy and Glucose Metabolism Reduced glycogen stores from caloric restriction and changes in insulin dynamics can leave patients with reduced exercise tolerance and potential for hypoglycemia, especially when food intake is inconsistent or protein/carbohydrate intake is inadequate
Diabetes Care 37 , 23172325 (2014)
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It also helps support immune function