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Bae JM, et al

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It does not invalidate the research, but it does mean human extrapolation should be conservative

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NascaCXenosDBaroneYCarusoAScaccianoceSMatriscianoFet alL-Acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of Mglu2 receptors

It suppresses ECM degradation, counteracts RSL3 mediated inhibition of GPX4, increases intracellular GSH levels and the GSH/GSSG ratio, reduces MDA content, and inhibits activation of the MAPK/NF-KB pathways, thereby protecting chondrocytes from ferroptosis (156)