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Smoking, poor diet, and chronic stress all deplete your body's natural antioxidant stores
This reaction is essentially a reversal of the thiolase (HADHB or ACAA2) catalyzed reaction of fatty acid -oxidation but is in fact catalyzed by the mitochondrial enzyme acetoacetyl-CoA thiolase (encoded by the ACAT1 gene)
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It has been reported that APP promotes the expression of PTEN result in the inhibition of PP2A and the accumulation of tau protein in AD model (Goiran et al
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