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Before termination of treatment, cells were incubated with 5 M MitoSOX for 15 min at 37 C, and washed in PBS
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For example, in alveolar macrophages, GLP-1 receptor agonism suppressed activation of the NLRP3 inflammasome and reduced production of IL-1 [65], an effect in part mediated by the disruption of histone lactylation, a recognised regulator of pro-fibrotic gene expression [65]
Researchers commonly investigate this peptide combination in studies involving
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