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After chronic infusion of Ang-II for 28 days, mice displayed a marked increase in systolic blood pressure (SBP) and diastolic blood pressure (DBP), compared to vehicle-infused mice (Fig
10.14670/hh-18-733 133 YangX.LiuY.ZhongC.HuJ.XuS.ZhangP.et al (2023a)
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Notably, p53 activates PCDHB14 and inhibits SLC7A11 expression by enhancing p65 protein ubiquitination-mediated degradation, thereby abrogating p65 bind to the SLC7A11 promoter (Zhao et al., 2022)
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