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For example: A meta-analysis of 76 randomized trials found that use of GLP-1 receptor agonists (the drug class Ozempic belongs to) raises the risk of gallbladder and biliary diseasesespecially at higher doses or over longer durationswith relative risks ranging from 1.27 to 1.55 depending on the condition

Many people experience nausea, vomiting, and diarrhea when they first start taking semaglutide

Make sure youre drinking enough fluids every day

Keep a record of any skin changes and show your provider photos if reactions recur

However, severe gastrointestinal side effects might affect oral contraceptive absorption

To understand what that means for safety, see the treatment options section