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Overall, these molecules play vital roles in the bodys antioxidant defenses, detoxification of xenobiotics, modulation of redox-controlled signaling pathways, and regulation of cellular proliferation and apoptosis

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1995, Bruijn et al

The integration mechanism of NLRP3 inflammasome activation and the IL-1 signaling pathway, synergistically driving the inflammatory cascade response, is shown in Figure 1