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Standard chemoradiation for glioblastoma results in progressive brain volume loss
Semaglutide is a GLP-1 receptor agonist, the same class of medication marketed under brand names like Ozempic and Wegovy
We hypothesize that the influence of SFN on the gut microbiota is at least partly related to the effects on their habitat, i.e., the gut such as (i) alleviation of oxidative stress and inflammation in the intestine, (ii) increase of the expression of tight junction proteins, preventing excessive intestinal permeability and invasion of luminal bacteria, and (iii) promotion of gut detoxification capability via increase of activity of phase II detoxification enzymes such as GSTs
Long term use of beinaglutide, a recombinant human GLP-1(7-36) acid, was demonstrated to reduce the body weight and improve steatosis (194)
Kay Pepin Vlad Ratziu This is extremely exciting for people living with MASH & MAFLD
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