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Special Considerations for Specific CKD Populations Dosing in Advanced CKD and Dialysis For patients with advanced CKD or those on dialysis, GLP-1 therapy is an option, but dosing requires extra care
Palmitic, oleic, linoleic or linolenic acid dose-dependently stimulated active GLP-1 secretion from cells
It rinses away cleanly with water after application
Separately, in the REDEFINE 4 head-to-head trial against tirzepatide, CagriSema produced approximately 20.2% body weight reduction at 84 weeks, compared with 23.6% for tirzepatide