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These drugs are used to treat illnesses such as type 2 diabetes and obesity
375 However, PROTACs face translational challenges due to poor membrane permeability, instability, suboptimal pharmacokinetics, uneven tissue distribution, and limited specificity
S.VinyardB
The goal is to reach the FDA-approved maintenance dose, but holding at a submaximal level is preferable to discontinuation" [10]
Approximately 15-40% of individuals diagnosed with IBD and an additional 20-40% are estimated to be obese and overweight respectively ( Table 1 )
Med Sci Sports Exerc
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