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During GLP-1 treatment , maintain regular contact with your healthcare team and report: Any new or worsening anxiety symptoms , including excessive worry, panic attacks, or physical anxiety symptoms Changes in mood , sleep patterns, or appetite beyond expected treatment effects Difficulty coping with side effects such as nausea, which may exacerbate anxiety Concerns about body image or eating behaviours as weight changes occur NICE guidance recommends holistic care for people with diabetes and obesity, recognising the importance of psychological wellbeing

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doi:10.3389/fendo.2023.1121387 PMID: 37051199

But the list price isn't what most people actually pay

Quick Answer: There is no established clinical evidence that tirzepatide directly causes patients to become quieter or experience personality changes

They aren't studying the same thing at all