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For those incorporating Semaglutide into their weight loss plan, B-12 can complement this treatment by addressing potential fatigue or weakness associated with weight loss efforts

Neither compound has an FDA-approved use, so there is no regulatory efficacy or safety determination to lean on

The FDA is not legally bound by advisory committee recommendations and has previously diverged from PCAC consensus, though doing so is uncommon

Not every patient is a candidate, and therapy begins only when clinically appropriate

People who follow a vegan or vegetarian diet may be at risk of vitamin B12 deficiency

It's especially important that pregnant vegan women who are planning to breastfeed exclusively talk to their medical team about getting adequate vitamin B12 for both themselves and their infants