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NICE NG183) Seek a specialist allergy referral if: You have recurrent severe allergic reactions without a clearly identified trigger You are considering allergen immunotherapy (desensitisation) Your asthma or eczema remains poorly controlled despite standard treatments You are pregnant or breastfeeding and require allergy treatment, as some medicines require careful riskbenefit assessment Regular review of your allergy treatment plan by a healthcare professional ensures that your medicines remain appropriate, effective, and as safe as possible

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Therefore, GLP-1RA may target different pathways to control appetite and inflammatory processes which would contribute to the treatment of obesity