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Recent studies have shown that certain metastatic subpopulations exhibit a strong dependence on glutamine-driven TCA cycle activity, whereas others highly express FAO enzymes, maintain low levels of ROS, and display enhanced migratory capacity and immune evasion [40]

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They are also preferred by researchers who want to avoid injections entirely, though it is worth noting that the oral route distributes the peptide systemically rather than concentrating it at a specific site