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It usually starts shortly after the injection and, in most cases, resolves within 24 hours
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Ligand binding to TLRs typically recruits the adaptor protein myeloid differentiation primary response 88 (MyD88), thereby triggering major pro-inflammatory signaling cascades, including the MAPK and nuclear factor kappa B (NF-B) pathways (165, 259)
Diem, Ducluzeau, Scheen)
mean BMI was 28 kg/m2
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