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Dosing & Reconstitution Guide Subcutaneous, once or twice daily Subcutaneous Protocol (2 mL = 5 mg/mL) Frequency: Inject once or twice daily subcutaneously

It also activates the production of matrix metalloproteinases (MMP-2) involved in tissue remodeling, while inhibiting excessive pro-inflammatory MMPs

10.1016/j.jsbmb.2017.01.020 137

In some parts of the body, the injection often includes a local anesthetic (pain reliever) to start easing pain quickly