It was an early proof-of-concept trial with about 32 people who completed it, so the results are promising but preliminary (Depommier et al., 2019)
Notably, we observed increased levels of lytic cell death in NCI-H292, MDA-MB-468, FaDu and CAL-27 cells following X(PC) induction, especially in CAL-27 cells, which also has the highest CASP1 transcript levels among the tested cells (Extended Data Fig
Protein at meals (eggs, Greek yogurt, fish, poultry, tofu, tempeh, lentils, beans, lean meats) is among the better-studied nutrient stimuli for GLP-1 release and also aids satiety and muscle maintenance
Snyder, Y
The study was published in the Journal of the American Heart Association
The cognitive behavior impairment was also observed to be improved following ER stress inhibitor administration which clearly indicates the involvement of ER homeostasis in maintaining white matter injury