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Vitamin B12 plays a critical role in energy production by converting fats and carbohydrates into usable energy, helping combat fatigue, especially on a calorie-restricted diet

Wu et al., 2022)

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Plasma MDA (a lipid peroxidation marker) should decrease or remain stable despite ongoing weight loss if MDA rises while glutathione increases, oxidative stress exceeds antioxidant capacity and dosing adjustments are needed

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In a healthy, optimally functioning body, glutathione acts as the primary defense mechanism against reactive oxygen species (ROS), actively neutralizing free radicals before they can cause irreversible damage to cellular membranes, functional proteins, and mitochondrial DNA