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As of 2025, its still in phase-3 clinical trials by Eli Lilly
Pflanzenstoffe: Bestimmte Obst- und Gemsesorten enthalten Stoffe in hoher Konzentration, die die Glutathion-Enzyme aktivieren
In addition, Kim et al
Non-response at standard dosing often indicates either high baseline homocysteine (requiring twice-weekly dosing) or concurrent folate deficiency (impairing methionine-to-SAMe conversion)
It should be avoided in these circumstances
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