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Most people describe it as very tolerable, similar to a routine vaccination

How low B12 is tested for Confirming a B12 problem starts with a serum B12 blood test

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However, for exceptionally thin or muscular people with little subcutaneous fat, you may need to insert the needle at a 45-degree angle (diagonally) to avoid injecting it into muscle tissue

A mouse metabolises on a faster clock than a human, and a controlled diet in a cage is not a free-living human diet so even the week-numbers above should be read as the shape of a gradual response, not a promise that a human would see anything on the same calendar

This is why autoimmune gastritis B12 deficiency deserves more attention