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Downtime varies by modality

The minimum meaningful evaluation period is 46 months of consistent daily application

Future implications of sublingual formulations of GLP-1 receptor agonists As mentioned above, GLP-1 receptor agonists are approved for the treatment of T2D and (sometimes off label) used for the treatment of obesity

GLP-1 +6 May 29, 2026 10 min read The Super Bowl Conference for diabetes and incretins

Eat substantial food 2-3 hours beforehand, avoid driving for at least 4-5 hours afterward, and monitor for GI symptoms