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GLP-1 receptor agonists are licensed for type 2 diabetes and weight management, not menopausal symptoms These medications work by enhancing insulin secretion, suppressing glucagon, slowing gastric emptying, and reducing appetite Weight loss from GLP-1 therapy may theoretically influence vasomotor symptoms, but robust clinical trial evidence is lacking Hormone replacement therapy remains the most effective first-line treatment for moderate to severe hot flashes in the UK Common GLP-1 side effects include gastrointestinal symptoms, with risks of pancreatitis and gallbladder disease requiring monitoring Table of Contents What Are GLP-1 Medications and How Do They Work

Macrophages phenotype dictated by liraglutide and its effect on atherosclerosis was again researched by Bruen R, et al

Study has shown that changes in modern lifestyles have led to a decrease in the diversity of the gut microbiota in many developed populations (Clemente et al., 2015)

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For instance, living with obesity (a BMI of 30 or higher) can directly impact fertility, whereas reaching a healthier weight by using GLP-1s could help improve your chances of conceiving

Trial data led the FDA to issue a warning about an increased risk for HF for people with heart or kidney disease using alogliptin or saxagliptin (Onglyza, AstraZeneca) in 2016