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108 Similarly, combined inhibition of ABCB1 (MDR1) and the use of PROTACs targeting the KRAS and MAPK signaling pathways enhances the treatment response in KRAS-mutant colorectal cancer xenograft models

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As discussed, the interplay between astrocytes and microglia via modulation of GSH activity implies that GSH is not only a cellular antioxidant, but an important mediator of cross-talk between resident CNS immune cells

[Read More] Carroll PV, Christ ER, Umpleby AM, Gowrie I, Jackson N, Bowes SB, Hovorka R, Croos P, Snksen PH, Russell-Jones DL