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Plants 13(5):609

This matters for three reasons

The enzyme dipeptidyl peptidase 4 (DPP-IV) cleaves it between the second and third residues which renders it inactive within several minutes, and explains why GLP-1 cannot be used as a drug itself

An optimally functioning homocysteine pathway provides methyl and sulfur groups for biochemical reactions such as detoxification, healthy immune function, ideal joint and cartilage structure, and brain and cardiovascular health so its important to metabolize homocysteine effectively